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Product Details
CF809946
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1A6
Immunogen
Human recombinant protein fragment corresponding to amino acids 734-808 of human DGKZ produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 104 kDa diacylglycerol kinase; DAG kinase DAGK6; DAG kinase zeta; DGK-IV; DGK-zeta; Diacylglycerol kinase zeta; diacylglycerol kinase, zeta 104kDa; Diglyceride kinase zeta
Gene Aliases: DAGK5; DAGK6; DGK-ZETA; DGKZ; E130307B02Rik; ENSMUSG00000075035; F730209L11Rik; hDGKzeta; mDGK[z]
UniProt ID: (Human) Q13574, (Mouse) Q80UP3, (Rat) O08560
Entrez Gene ID: (Human) 8525, (Mouse) 104418, (Rat) 81821
protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
cell migration
platelet activation
intracellular signal transduction
mitotic G1 DNA damage checkpoint
negative regulation of catalytic activity
negative regulation of mitotic cell cycle
negative regulation of Ras protein signal transduction
lipid phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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