This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
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Protein Aliases: Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain-containing protein 1; Dixin
Gene Aliases: CCD1; DIXDC1; KIAA1735
UniProt ID: (Human) Q155Q3
Entrez Gene ID: (Human) 85458