Sequence of this protein is as follows: KIKKIMKNGE MPPEHSPSSS DPMACNSPQS PAVWEPQGSS RSLSHHPHAH PPTSNQSPAS SYLENSASWY TSAASSINSH LPPPGSLQH
This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
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Protein Aliases: distal-less homeo box 5; DLX-3; Homeobox protein DLX-3; Homeobox protein DLX-5; RDLX; split hand/foot malformation type 1 with sensorineural hearing loss
Gene Aliases: AI385752; DLX5; RDLX; SHFM1D
Molecular Function: homeodomain transcription factor