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Invitrogen
MA5-13249 targets DNA-PKcs in GS, IF, and IHC (P) applications and shows reactivity with Human samples.
The MA5-13249 immunogen is human DNA-dependent Protein Kinase purified from HeLa cells.
DNA-dependent Protein Kinase (DNA-PKcs) phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. In vivo, it is involved in repairing double strand DNA breaks
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: complementing 1; DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNPK1; hyper-radiosensitivity of murine scid mutation; hyper-radiosensitivity of murine scid mutation, complementing 1; p460
Gene Aliases: DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; PRKDC; XRCC7
UniProt ID: (Human) P78527
Entrez Gene ID: (Human) 5591
Molecular Function:
kinase
non-receptor serine/threonine protein kinase
nucleic acid binding
nucleotide kinase
protein kinase
transferase
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