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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.|
|Storage buffer||PBS, pH 7.2|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24221 detects DNA Polymerase Delta in Human samples.
MA1-24221 has been successfully used in Western Blot procedures.
MA1-24221 immunogen corresponds to Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d..
DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3' to 5' exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CDC2; CDC2 homolog; DNA polymerase delta catalytic subunit; DNA polymerase subunit delta p125; POLD; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit
CDC2; CRCS10; MDPL; POLD; POLD1