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Product Details
66587-1-IG
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:2,000-1:8,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Pig, Rat |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1A1D2 |
Immunogen |
DNAJB6 Fusion Protein Ag2258 (1-241 aa encoded by BC000177) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MVDYYEVLG VQRHASPEDI KKAYRKLALK WHPDKNPENK EEAERKFKQV AEAYEVLSDA KKRDIYDKYG KEGLNGGGGG GSHFDSPFEF GFTFRNPDDV FREFFGGRDP FSFDFFEDPF EDFFGNRRGP RGSRSRGTGS FFSAFSGFPS FGSGFSSFDT GFTSFGSLGH GGLTSFSSTS FGGSGMGNFK SISTSTKMVN GRKITTKRIV ENGQERVEVE EDGQLKSLTI NGKEQLLRLD NK (1-241 aa encoded by BC000177)
Target Information
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ homolog subfamily B member 6; DnaJ-like 2 protein; dnajb6 {ECO:0000312|EMBL:AAH78908.1, ECO:0000312|RGD:1308207}; Heat shock protein J2; HHDJ1; HSJ-2; Hsp40 homolog; mammalian relative of DnaJ; mDj4; MRJ; MSJ-1
Gene Aliases: DJ4; DnaJ; DNAJB6; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; mDj4; MRJ; MSJ-1; MSJ1
UniProt ID: (Human) O75190, (Mouse) O54946, (Rat) Q6AYU3
Entrez Gene ID: (Human) 10049, (Pig) 100525669, (Mouse) 23950, (Rat) 362293
protein folding
actin cytoskeleton organization
extracellular matrix organization
positive regulation of ATPase activity
regulation of protein localization
protein localization to nucleus
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
intermediate filament organization
negative regulation of transcription, DNA-templated
chorio-allantoic fusion
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
chorion development
negative regulation of inclusion body assembly
regulation of cellular response to heat
chaperone-mediated protein folding
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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