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Product Details
H00054431-M02A
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
ELISA (ELISA) |
10 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG1, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
3A8 |
Immunogen |
DNAJC10 (NP_061854, 688 a.a. approximately 793 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
See Label |
Storage buffer |
ascites |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Sequence of this protein is as follows: KNHWVIDFYA PWCGPCQNFA PEFELLARMI KGKVKAGKVD CQAYAQTCQK AGIRAYPTVK FYFYERAKRN FQEEQINTRD AKAIAALISE KLETLRNQGK RNKDEL
Target Information
This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. DNAJC10 may act as a co-chaperone for HSPA5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DnaJ (Hsp40) homolog, subfamily C, member 10; DnaJ homolog subfamily C member 10; Endoplasmic reticulum DNA J domain-containing protein 5; Endoplasmic reticulum DnaJ-PDI fusion protein 1; ER-resident protein ERdj5; J domain-containing PDI-like protein; J domain-containing protein disulfide isomerase-like protein; J-domain-containing protein disulfide isomerase-like protein; Macrothioredoxin; MTHr; protein disulfide isomerase family A, member 19
Gene Aliases: 1200006L06Rik; D2Ertd706e; DNAJC10; ERDJ5; JPDI; MTHr; PDIA19; UNQ495/PRO1012
UniProt ID: (Human) Q8IXB1, (Rat) Q498R3, (Mouse) Q9DC23
Entrez Gene ID: (Human) 54431, (Rat) 295690, (Mouse) 66861
Molecular Function:
chaperone
negative regulation of protein phosphorylation
ER-associated ubiquitin-dependent protein catabolic process
positive regulation of ATPase activity
protein folding in endoplasmic reticulum
response to endoplasmic reticulum stress
cell redox homeostasis
oxidation-reduction process
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
ATPase activator activity
protein binding
protein disulfide oxidoreductase activity
disulfide oxidoreductase activity
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Hsp70 protein binding
chaperone binding
ATPase binding
misfolded protein binding
peptide-methionine (S)-S-oxide reductase activity
oxidoreductase activity
peptide-methionine (R)-S-oxide reductase activity
methionine-R-sulfoxide reductase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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