|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||This antibody was raised against the first 10 kDa of the N-terminus of the DNMT1 protein.|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-dependent|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-32315 detects DNMT1 from human samples.
PA1-32315 has been successfully used in immunoprecipitation, Western blot applications.
The PA1-32315 immunogen is: This antibody was raised against the first 10 kDa of the N-terminus of the DNMT1 protein.
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.