Invitrogen

DOPA Decarboxylase Monoclonal Antibody (10H9E8E7)

Product Details

Tested Applications

Dilution

ELISA (ELISA)

1:1000-1:2000

Product Specifications

Species Reactivity

Human

Host / Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

10H9E8E7

Immunogen

Recombinant Human DDC protein

Conjugate

Unconjugated

Form

Liquid

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human DDC/AADC.

Target Information

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: AADC; aromatic L-amino acid decarboxylase; aromatic L-amino decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase)

Gene Aliases: AADC; DDC

UniProt ID: (Human) P20711

Entrez Gene ID: (Human) 1644

Molecular Function: decarboxylase lyase