Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
ELISA (ELISA) |
1:1,000-1:2,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2b |
Class |
Monoclonal |
Type |
Antibody |
Clone |
10H9E8E7 |
Immunogen |
Recombinant Human DDC protein (Met1-Glu480) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS |
Contains |
no preservative |
Storage conditions |
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
RRID |
AB_2786206 |
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human DDC/AADC.
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AADC; aromatic L-amino acid decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719
Gene Aliases: AADC; DDC
UniProt ID: (Human) P20711
Entrez Gene ID: (Human) 1644
Molecular Function:
decarboxylase
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