|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 19 publications below|
|Tested Species reactivity||Yeast|
|Published species reactivity||Yeast|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Yeast Dolichol phosphate mannose synthase|
|Storage buffer||HEPES buffered saline|
|Contains||0.02% sodium azide|
|Storage conditions||4° C|
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDGIE; dolichol monophosphate mannose synthase; Dolichol-phosphate mannose synthase; Dolichol-phosphate mannosyltransferase; Dolichyl-phosphate beta-D-mannosyltransferase; DPM synthase; Mannose-P-dolichol synthase; MPD synthase; MPDS
Gene Aliases: DPM1; P9705.3; SED3; YPR183W
UniProt ID: (Baker's yeast) P14020
Entrez Gene ID: (Baker's yeast) 856313
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