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Invitrogen
DRD5 Recombinant Rabbit Monoclonal Antibody (HL3081)
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FIGURE: 1 / 4
DRD5 Antibody (MA5-56686) in ICC/IF
Immunocytochemistry analysis of DRD5 using DRD5 Recombinant Monoclonal Antibody (Product # MA5-56686) in SH-SY-5Y cells fixed in ice-cold MeOH for 5 min. DRD5 antibody diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody (Product # MA5-31466) Blue: Fluoroshield with DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-56686
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL3081
Immunogen
Synthetic peptide encompassing a sequence within the Intracellular domain of human Dopamine Receptor D5. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: d(5) dopamine receptor; D1b receptor; D1beta dopamine receptor; Dopamine 5 receptor; dopamine D5 receptor; dopamine receptor 5; dopamine receptor D1B; DRD 1B; DRD 5; G protein-coupled receptor DRD5; Hd5dr; MGC10601; unnamed protein product
Gene Aliases: D5R; DBDR; Drd-5; DRD1B; DRD1L2; Gpcr1
UniProt ID: (Human) P21918, (Mouse) Q8BLD9
Entrez Gene ID: (Human) 1816, (Mouse) 13492
synaptic transmission, dopaminergic
response to amphetamine
regulation of systemic arterial blood pressure by vasopressin
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
negative regulation of protein kinase activity
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
dopamine receptor signaling pathway
mating behavior
regulation of blood pressure
associative learning
visual learning
transmission of nerve impulse
negative regulation of cell migration
wound healing
response to cocaine
positive regulation of MAPK cascade
negative regulation of blood pressure
regulation of female receptivity
sensitization
long term synaptic depression
cellular response to catecholamine stimulus
adenylate cyclase-activating adrenergic receptor signaling pathway
reactive oxygen species metabolic process
regulation of postsynaptic membrane neurotransmitter receptor levels
cellular calcium ion homeostasis
chemical synaptic transmission
positive regulation of adenylate cyclase activity
phospholipase C-activating dopamine receptor signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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