The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
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Protein Aliases: Actin-depolymerizing factor; ADF; bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP)); Destrin; destrin (actin depolymerizing factor); epididymis luminal protein 32; RP23-77A2.1; sID
Gene Aliases: ACTDP; ADF; bA462D18.2; DSN; DSTN; HEL32
UniProt ID: (Human) P60981
Molecular Function: non-motor actin binding protein