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|Tested species reactivity||Dog, Horse, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (573 SRSSGSNRSGSDRRKEKD 590) of DVL-3 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Dishevelled-3 (DVL-3) is a cytoplasmic phoshoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes including segmentation and neuroblast specification in Drosophila. It is known to play a crucial role in WNT canonical signaling pathway and has been shown to be a connecting link between the Notch-WNT crosstalk. The structural and evolutionary characteristics suggest that mutations at their loci may be involved in neural and heart development defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dishevelled 3 (homologous to Drosophila dsh); dishevelled 3, dsh homolog; dishevelled, dsh homolog 3; Dishevelled-3; DSH homolog 3; Segment polarity protein dishevelled homolog DVL-3
DRS3; DVL3; KIAA0208