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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Disheveled DVL2 is a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
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Protein Aliases: dishevelled 2 (homologous to Drosophila dsh); dishevelled, dsh homolog 2; Dishevelled-2; DSH homolog 2; Segment polarity protein dishevelled homolog DVL-2
Gene Aliases: DVL2
UniProt ID: (Human) O14641
Entrez Gene ID: (Human) 1856
Molecular Function: scaffold/adaptor protein