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Abnova
DVL3 Monoclonal Antibody (4H2)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
H00001857-M04
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
4H2
Immunogen
DVL3 (AAH32459, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.47 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MGETKIIYHL DGQETPYLVK LPLPAERVTL ADFKGVLQRP SYKFFFKSMD DDFGVVKEEI SDDNAKLPCF NGRVVSWLVS AEGSHPDPAP FCADNPSELP
Target Information
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila disheveled gene, dsh. The Drosophila disheveled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytoplasmic phosphoprotein; dishevelled 3 (homologous to Drosophila dsh); dishevelled, dsh homolog 3; dvl-3; KIAA0208; OTTHUMP00000210778; unnamed protein product
Gene Aliases: DRS3
UniProt ID: (Human) Q92997
Entrez Gene ID: (Human) 1857
small GTPase mediated signal transduction
Wnt signaling pathway
regulation of protein localization
regulation of actin cytoskeleton organization
intracellular signal transduction
non-canonical Wnt signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
protein stabilization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
positive regulation of neuron projection arborization
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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