Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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Protein Aliases: Cytoplasmic dynein 1 light intermediate chain 1; DLC-A; Dynein light chain A; Dynein light intermediate chain 1, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 1; LIC1
Gene Aliases: DLC-A; DNCLI1; DYNC1LI1; LIC1
UniProt ID: (Human) Q9Y6G9
Entrez Gene ID: (Human) 51143
Molecular Function: microtubule or microtubule-binding cytoskeletal protein