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Immunofluorescent analysis of DYX1C1 showing staining in the nucleus of H1299 cells. H1299 cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a DYX1C1 polyclonal antibody (Product # PA5-31138) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10µm.
|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 183 and 406 of Human DYX1C1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31138 targets DYX1C1 in WB applications and shows reactivity with Human samples.
The PA5-31138 immunogen is recombinant protein fragment corresponding to a region within amino acids 183 and 406 of Human DYX1C1.
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dynein, axonemal, assembly factor 4; dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYXC1; EKN1; RD
CILD25; DNAAF4; DYX1; DYX1C1; DYXC1; EKN1; RD