Immunogen sequence: KLKEDSIPAP RSVGSIKINF TPRVFPTALR ESQVAEEEEW LHKQAEARRA MNTDIAELCD LKEEEKNPEW LKDKGNKLFA TENYLAAINA
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dynein axonemal assembly factor 4; dynein, axonemal, assembly factor 4; Dyslexia susceptibility 1 candidate gene 1 protein; FLJ37882; MGC70618
Gene Aliases: CILD25; DNAAF4; DYX1; DYX1C1; DYXC1; EKN1; RD
UniProt ID: (Human) Q8WXU2
Entrez Gene ID: (Human) 161582
Molecular Function: chaperone