Exalpha

Degenerative Spermatocyte Homolog 1 (DEGS1) Polyclonal Antibody

View all (12) DEGS1 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

X2090P

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide derived from the human DEGS1 protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-2 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

0.08% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive control: Placenta.

Target Information

The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4 ) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulation biosynthetic processing of the EGF receptor. Two splice variants have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; degenerative spermatocyte homolog 1, lipid desaturase; degenerative spermatocyte homolog, lipid desaturase; Degenerative spermatocyte-like protein RDES; Delta(4)-desaturase; delta(4)-desaturase, sphingolipid 1; dihydroceramide desaturase; dihydroceramide desaturase 1; Dihydroceramide desaturase-1; DSH1; membrane fatty acid (lipid) desaturase; Membrane lipid desaturase; MGC5079; migration-inducing gene 15 protein; Retinol isomerase; sphingolipid 1; sphingolipid delta 4 desaturase; sphingolipid delta(4)-desaturase 1; Sphingolipid delta(4)-desaturase DES1

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Gene Aliases: AA536663; DEGS; DEGS-1; DEGS1; Des-1; DES1; FADS7; Mdes; MIG15; MLD

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UniProt ID: (Human) O15121, (Mouse) O09005, (Rat) Q5XIF5

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Entrez Gene ID: (Human) 8560, (Mouse) 13244, (Rat) 58970

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Function(s)
electron carrier activity sphingolipid delta-4 desaturase activity oxidoreductase activity fluorene oxygenase activity mono-butyltin dioxygenase activity tri-n-butyltin dioxygenase activity di-n-butyltin dioxygenase activity methylsilanetriol hydroxylase activity methyl tertiary butyl ether 3-monooxygenase activity 4-nitrocatechol 4-monooxygenase activity 4-chlorophenoxyacetate monooxygenase activity tert-butanol 2-monooxygenase activity alpha-pinene monooxygenase activity dimethylsilanediol hydroxylase activity ammonia monooxygenase activity hydroxymethylsilanetriol oxidase activity 2-hydroxyisobutyrate 3-monooxygenase activity alpha-pinene dehydrogenase activity bisphenol A hydroxylase B activity 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity 9-fluorenone-3,4-dioxygenase activity anthracene 9,10-dioxygenase activity 2-(methylthio)benzothiazole monooxygenase activity 2-hydroxybenzothiazole monooxygenase activity benzothiazole monooxygenase activity 2,6-dihydroxybenzothiazole monooxygenase activity pinacolone 5-monooxygenase activity thioacetamide S-oxygenase activity thioacetamide S-oxide S-oxygenase activity endosulfan monooxygenase I activity N-nitrodimethylamine hydroxylase activity 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity endosulfan ether monooxygenase activity pyrene 4,5-monooxygenase activity pyrene 1,2-monooxygenase activity 1-hydroxypyrene 6,7-monooxygenase activity 1-hydroxypyrene 7,8-monooxygenase activity phenylboronic acid monooxygenase activity spheroidene monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen hydroxylase
Process(es)
unsaturated fatty acid biosynthetic process sphingolipid biosynthetic process ceramide biosynthetic process oxidation-reduction process lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process positive regulation of apoptotic process
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