|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Immunocytochemistry (ICC)||See 11 publications below|
|Immunohistochemistry (IHC)||See 45 publications below|
|Flow Cytometry (Flow)||See 3 publications below|
|Tested Species reactivity||Bovine, Dog, Chicken, Cat, Hamster, Human, Non-human primate, Rat|
|Published species reactivity||Dog , Rabbit , Rat , Non-human primate , Sheep , Cat , Human , Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Desmin from human muscle|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-13259 targets Desmin in IF and IHC (P) applications and shows reactivity with Bovine, Canine, Chicken, Feline, Hamster, Human, Non-human primate, and Rat samples.
The MA5-13259 immunogen is desmin from human muscle.
Desmin is an intermediate filament protein of both smooth and striated muscles. Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. Anti-desmin antibody is useful in identification of tumors of myogenic origin. It reacts with leiomyosarcomas (smooth muscle) as well as rhabdomyosarcomas (striated muscle).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Desmin; desmin-like protein; intermediate filament protein; mutant desmin p.K241E
Gene Aliases: BOS_2078; CSM1; CSM2; DES; I79_018932; LGMD2R
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.