This Antibody was verified by Peptide array to ensure that the antibody binds to the antigen stated. View Details
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with di-methylated histone H3 Lys4, Lys9, Lys27, Lys79 or methylated histone H4 Lys20.
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H3 histone family, member A; H3 histone family, member C; H3 histone family, member H; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3a; H3K36me2; H3L-like histone; HIST1H3A; Histone 1; histone 1, H2ai; histone 1, H3a; histone 1, H3b; histone 1, H3c; histone 1, H3f; histone 1, H3g; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; histone cluster 1, H2ai; histone cluster 1, H2ai-like; histone cluster 1, H3a; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone cluster 3, H3; histone gene complex 1; histone H3; Histone H3.1; Histone H3.2; Histone H3.3; histone H3.3B-like; Histone H3.3C; Histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; Histone H3/m; Histone H3/o; histone variant H3.5; histone1, H3c
Gene Aliases: 9430068D06Rik; H3; H3 histone; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3-B; H3-F; H3.1; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/c; H3/h; H3/i; H3/k; H3/l; H3/M; H3/n; H3/o; H3a; H3b; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; Hist1; Hist1h2ai; Hist1h2ail; HIST1H3A; HIST1H3B; Hist1h3c; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; M32460; M32461; PP781
UniProt ID: (Human) P84243, (Human) P84243, (Human) Q6NXT2, (Mouse) P84244, (Mouse) P84244, (Rat) P84245, (Human) P68431, (Human) Q6NWP8, (Human) P68431, (Human) P68431, (Human) P68431, (Human) P68431, (Human) Q71DI3, (Human) Q71DI3, (Rat) Q6LED0, (Rat) Q6LED0, (Mouse) P84228, (Mouse) P84228, (Mouse) P84228, (Mouse) P68433, (Mouse) P68433, (Mouse) P84228
Entrez Gene ID: (Human) 3020, (Human) 3021, (Human) 440093, (Mouse) 15078, (Mouse) 15081, (Rat) 117056, (Rat) 100360868, (Human) 8350, (Human) 8358, (Human) 8352, (Human) 8968, (Human) 8355, (Human) 8357, (Human) 333932, (Human) 126961, (Rat) 291159, (Rat) 679994, (Mouse) 319150, (Mouse) 319148, (Mouse) 260423, (Mouse) 97908, (Mouse) 319152, (Mouse) 97114, (Rat) 310678