|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (GSTLPVEGGFWAC) corresponding to the C-terminus amino acids of DCXR|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: carbonyl reductase; carbonyl reductase 2; Carbonyl reductase II; DCR; Dicarbonyl/L-xylulose reductase; HCR2; HCRII; human carbonyl reductase 2; KIDCR; Kidney dicarbonyl reductase; L-xylulose reductase; P34H; SDR20C1; Short chain dehydrogenase/reductase family 20C member 1; short chain dehydrogenase/reductase family 20C, member 1; Sperm surface protein P34H; XR
Gene Aliases: DCR; DCXR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR
UniProt ID: (Human) Q7Z4W1
Entrez Gene ID: (Human) 51181
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