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|Tested species reactivity||Fruit fly|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from residues 900 - 1000 Dicer (Dcr1).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-19429 targets Dicer in WB applications and shows reactivity with Drosophila samples.
The PA5-19429 immunogen is synthetic peptide derived from residues 900 - 1000 Dicer (Dcr1).
PA5-19429 detects Dicer which has a predicted molecular weight of approximately 255 kDa.
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CG4792-PA; Dcr-1-PA; DCR1, Dicer, HERNA, KIAA0928, Dicer1, Dcr-1 homolog; dicer; dicer 1; dicer 1, double-stranded RNA-specific endoribonuclease; Dicer-1; dicer1; endoribonuclease Dicer; helicase MOI; helicase with RNAse motif; helicase-moi; K12H4.8-LIKE
CG4792; Dcr; dcr 1; DCR-1; DCR1; DICER; dicer-1; Dicer1; Dmel\CG4792; Dmel_CG4792