|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from internal region of human DPP10.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Panda, Bovine, Dog, Horse, Guinea pig (100%).
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dipeptidyl peptidase 10; Dipeptidyl peptidase IV-related protein 3; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; Dipeptidyl-peptidase 10; dipeptidyl-peptidase 10 (inactive); dipeptidyl-peptidase 10 (non-functional); Dipeptidylpeptidase 10; DPL2; DPP X; DPP10; DPPY; DPRP-3; DPRP3; Inactive dipeptidyl peptidase 10; KIAA1492
Gene Aliases: DPL2; DPP10; DPPY; DPRP-3; DPRP3; KIAA1492
UniProt ID: (Human) Q8N608
Entrez Gene ID: (Human) 57628
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