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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 223 and 550 of Human Dishevelled 2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27965 targets Dishevelled 2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27965 immunogen is recombinant fragment corresponding to a region within amino acids 223 and 550 of Human Dishevelled 2.
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dishevelled 2 (homologous to Drosophila dsh); dishevelled, dsh homolog 2; dishevelled-2; DSH homolog 2; segment polarity protein dishevelled homolog DVL-2