PA1-18314 detects DBH from human, rat, guinea pig, and bovine samples.
PA1-18314 has been successfully used in immunohistochemistry, Western blot, radioimmune assay, and inhibition assay procedures.
The PA1-18314 immunogen is native enzyme prepared from bovine adrenal glands.
After reconstitution, store aliquots at -20 C or 4 C with appropriate antibacterial agent. Avoid freeze/thaw cycles.
Reconstitute with 100 µL of distilled water.
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dopamine beta hydroxylase (dopamine beta-monooxygenase); Dopamine beta-hydroxylase; dopamine beta-hydroxylase (dopamine beta-monooxygenase); dopamine beta-hydroxylase precursor (EC 22.214.171.124); Dopamine beta-monooxygenase; dopamine beta-monooxygenase precursor (EC 126.96.36.199); Dopamine-Beta-hydroxylase; mixed function oxidase; Soluble dopamine beta-hydroxylase
Gene Aliases: DBH; DBM; DOPBHY