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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues surrounding His549 of human Drosha|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Contains||<0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
It is not recommended to aliquot this antibody.
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
drosha, double-stranded RNA-specific endoribonuclease; drosha, ribonuclease type III; ethanol induced 2; nuclear RNase III Drosha; OTTHUMP00000220910; OTTHUMP00000220911; OTTHUMP00000220912; OTTHUMP00000220913; p241; protein Drosha; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; ribonuclease 3; ribonuclease III, nuclear; ribonuclease type III, nuclear; RNase III
1110013A17Rik; AI874853; DROSHA; ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN