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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human Dsk2|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with mouse and rat based on sequence homology.
Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
hPLIC-2; HRIHFB2157; Nedd4 binding protein 4; PLIC-2; protein linking IAP with cytoskeleton 2; Protein linking IAP with cytoskeleton-2; Ubiquilin 2; ubiquitin-like product Chap1/Dsk2
ALS15; CHAP1; DSK2; HRIHFB2157; N4BP4; PLIC2; UBQLN2