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Invitrogen
Dynamin 3 Recombinant Rabbit Monoclonal Antibody (23GB5175)
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FIGURE: 1 / 2
Dynamin 3 Antibody (MA5-52808) in ICC/IF
Immunocytochemistry analysis of Dynamin 3 in HeLa cells. Sample was incubated with Dynamin 3 monoclonal (Product # MA5-52808) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-52808
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB5175
Immunogen
A synthesized peptide derived from human Dynamin 3 (750-800AA).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dynamin family member; dynamin III; dynamin, testicular; GTPase; SH3-binding protein; T-dynamin; testicular dynamin; unnamed protein product
Gene Aliases: 9630020E24Rik; B230343F03Rik; C530045C17; Dyna III; dynamin-2; mKIAA0820
UniProt ID: (Human) Q9UQ16, (Mouse) Q8BZ98, (Rat) Q08877
Entrez Gene ID: (Human) 26052, (Mouse) 103967, (Rat) 171574
GTPase activity
protein binding
GTP binding
microtubule binding
identical protein binding
type 1 metabotropic glutamate receptor binding
type 5 metabotropic glutamate receptor binding
nitric-oxide synthase binding
structural constituent of postsynapse
protein serine/threonine kinase binding
G-protein coupled receptor binding
endocytosis
synapse assembly
synaptic vesicle budding from presynaptic endocytic zone membrane
filopodium assembly
synaptic vesicle endocytosis
positive regulation of filopodium assembly
regulation of dendritic spine morphogenesis
negative regulation of dendritic spine morphogenesis
postsynapse organization
positive regulation of synaptic vesicle recycling
sperm ejaculation
positive regulation of cellular component organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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