Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG2a|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.
AHS6211 was used in flow cytometry to study the contribution of genes involved in the synthesis of sialyl-Lewis x to breast cancer.
|Julien S,Ivetic A,Grigoriadis A,QiZe D,Burford B,Sproviero D,Picco G,Gillett C,Papp SL,Schaffer L,Tutt A,Taylor-Papadimitriou J,Pinder SE,Burchell JM||Cancer research (71:7683)||2011|
Dendritic cell adhesion to cerebral endothelium: role of endothelial cell adhesion molecules and their ligands.
AHS6211 was used in blocking assay to investigate DC trafficking to the central nervous system.
|Arjmandi A,Liu K,Dorovini-Zis K||Journal of neuropathology and experimental neurology (68:300)||2009|
|Not Applicable||Not Cited||
Integrated pathways for neutrophil recruitment and inflammation in leprosy.
AHS6211 was used in immunohistochemistry - frozen section to identify genes involved in neutrophil recruitment in the lesions from patients with erythema nodosum leprosum
|Lee DJ,Li H,Ochoa MT,Tanaka M,Carbone RJ,Damoiseaux R,Burdick A,Sarno EN,Rea TH,Modlin RL||The Journal of infectious diseases (201:558)||2010|
|Not Applicable||Not Cited||
Immunological and ultrastructural characterization of endothelial cell cultures differentiated from human cord blood derived endothelial progenitor cells.
AHS6211 was used in flow cytometry to assess the ability of endothelial progenitor cells to differentiate into early mature endothelial cells
|Neumüller J,Neumüller-Guber SE,Lipovac M,Mosgoeller W,Vetterlein M,Pavelka M,Huber J||Histochemistry and cell biology (126:649)||2006|
|Human||Not Cited||Estimating the efficiency of cell capture and arrest in flow chambers: study of neutrophil binding via E-selectin and ICAM-1.||Zhang Y,Neelamegham S||Biophysical journal (83:1934)||2002|
CD62 antigen-like family member E; CD62E; E-selectin; ELAM; ELAM-1; ELAM1; endothelial adhesion molecule 1; Endothelial leukocyte adhesion molecule 1; ESEL; LECAM2; leukocyte endothelial cell adhesion molecule 2; Leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2
CD62E; ELAM; ELAM1; ESEL; LECAM2; SELE