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Human Umbilical Vein Endothelial Cells (HUVEC) were activated with Human TNF alpha Recombinant Protein and stained with Mouse IgG1 kappa Isotype Control PE (open histogram) or Anti-Human CD62E (E-Selectin) PE (filled histogram, A16340). Total viable cells were used for analysis.
|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD62 antigen-like family member E; CD62E; ELAM; ELAM-1; ELAM1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; ESEL; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2
CD62E; ELAM; ELAM1; ESEL; LECAM2; SELE