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|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Recombinant human EB-1 protein|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Contains||<0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
It is not recommended to aliquot this antibody.
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
adenomatous polyposis coli-binding protein EB1; APC-binding protein EB1; EB1; End-binding protein 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein, RP/EB family, member 1