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      View (2) other ECH1 antibodies

      Invitrogen

      ECH1 Monoclonal Antibody (9D11AF3)

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      Catalog #:A21972

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      Product Details

      TESTED APPLICATIONS DILUTION
      ELISA (ELISA) Assay Dependent
      Immunocytochemistry (ICC) 4 ug/ml
      Immunoprecipitation (IP) Assay Dependent
      Tested Species reactivity Human, Rat
      Host / Isotype Mouse / IgG1
      Class Monoclonal
      Type Antibody
      Clone 9D11AF3
      Immunogen ECH1 contains a C-terminal peroxisomal targeting sequence and localizes to the peroxisome
      Conjugate Unconjugated
      Form Liquid
      Concentration 1 mg/ml
      Purification purified
      Storage buffer HEPES buffered saline
      Contains 0.02% sodium azide
      Storage conditions 4° C
      RRID AB_2535884

      Background/Target Information

      This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      Bioinformatics

      Protein Aliases: 4)-dienoyl-CoA isomerase; 4-dienoyl-CoA isomerase; 5)-Delta(2; 5-delta2; delta(3; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; delta3; delta3,5-delta2,4-dienoyl-CoA isomerase; delta3,5-delta2,4-dienoyl-coenzyme A isomerase; dienoyl-CoA isomerase; enoyl CoA hydratase 1, peroxisomal; enoyl Coenzyme A hydratase 1; enoyl Coenzyme A hydratase 1, peroxisomal; enoyl hydratase-like protein peroxisomal; enoyl hydratase-like protein, peroxisomal; enoyl-CoA hydratase 1, peroxisomal; HPXEL; mitochondrial; peroxisomal; Peroxisomal enoyl hydratase-like protein; peroxisomal enoyl-CoA hydratase 1

      Gene Aliases: ECH1; HPXEL; Pxel

      UniProt ID: (Human) Q13011, (Rat) Q62651

      Entrez Gene ID: (Human) 1891, (Rat) 64526

      Molecular Function: acetyltransferase acyltransferase dehydrogenase epimerase/racemase hydratase isomerase ligase lyase oxidoreductase transferase

      Suggested Secondary Antibodies

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