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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the C-terminal of human EDG7.|
|Purification||Ammonium sulfate precipitation|
|Contains||0.08% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Due to low expression of EDG receptors, it is recommended to use Femto Signal Substrate for Western blot. A suggested positive control for this product is RH7777 cells transfected with EDG7.
EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
calcium-mobilizing lysophosphatidic acid receptor LP-A3; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; LPA receptor 3; LPA receptor EDG7; LPA-3; LPA3; lysophosphatidic acid receptor Edg-7
Edg-7; EDG7; GPCR; HOFNH30; LP-A3; LPA3; LPAR3; RP4-678I3