The calculated molecular weight of EEF1D is 31 kDa, but the modified protein is about 35-40 kDa.
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antigen NY-CO-4; EEF 1D; EF 1 delta; EF 1D; EF-1-delta; Elongation factor 1-delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); guanine nucleotide exchange protein; translation elongation factor 1-delta subunit
Gene Aliases: EEF1D; EF-1-delta; EF-1D; EF1D; FP1047