|Flow Cytometry (Flow)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||See 5 publications below|
|ChIP assay (ChIP)||See 1 publications below|
|Neutralization (Neu)||See 2 publications below|
|Immunocytochemistry (ICC)||See 3 publications below|
|Flow Cytometry (Flow)||See 7 publications below|
|ELISA (ELISA)||See 1 publications below|
|Immunoprecipitation (IP)||See 17 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Dog, Human|
|Published species reactivity||Rat , Non-human primate , Human , Mouse|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Purified EGFR from A431 cells|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12872 targets Epidermal Growth Factor Receptor in FACS and IP applications and shows reactivity with Canine and Human samples.
The MA5-12872 immunogen is purified EGFR from A431 cells.
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth f; Epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); erb-b2 receptor tyrosine kinase 1; ERBB; ERBB1; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Gene Aliases: EGFR; ERBB; ERBB1; HER1; mENA; NISBD2; PIG61
UniProt ID: (Human) P00533
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