Response of human cancer cells to simultaneous treatment with sorafenib and radiofrequency current.
Hernández-Bule ML,Martínez MA,Trillo MÁ,Martínez L,Toledano-Macías E,Úbeda A
Published figure using EGFR monoclonal antibody (Product # MA5-13877) in Western Blot
Mon Nov 01 00:00:00 EDT 2021
Molecular Correlates of In Vitro Responses to Dacomitinib and Afatinib in Bladder Cancer.
Bladder cancer (Amsterdam, Netherlands)
Tamura S,Wang Y,Veeneman B,Hovelson D,Bankhead A,Broses LJ,Lorenzatti Hiles G,Liebert M,Rubin JR,Day KC,Hussain M,Neamati N,Tomlins S,Palmbos PL,Grivas P,Day ML
MA5-13877 was used in western blotting to detect levels of EGFR in bladder cancer cell lines.
Sat Jan 20 00:00:00 EST 2018
Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.
Wu Y,Wang Y,Lin Y,Liu Y,Wang Y,Jia J,Singh P,Chi YI,Wang C,Dong C,Li W,Tao M,Napier D,Shi Q,Deng J,Evers BM,Zhou BP
MA513877 was used in immunocytochemistry and western blot to test if Dub3 contributes to Snail1 stability in cancer cells
Wed Feb 15 00:00:00 EST 2017
HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone.
Day KC,Lorenzatti Hiles G,Kozminsky M,Dawsey SJ,Paul A,Broses LJ,Shah R,Kunja LP,Hall C,Palanisamy N,Daignault-Newton S,El-Sawy L,Wilson SJ,Chou A,Ignatoski KW,Keller E,Thomas D,Nagrath S,Morgan T,Day ML
MA513877 was used in western blot to suggest that EGFR promotes survival of prostate tumor-initiating cells and circulating tumor cells that metastasize to bone, whereas HER2 supports the growth of prostate cancer cells once they are established at metastatic sites
Sun Jan 01 00:00:00 EST 2017
MUC1 stimulates EGFR expression and function in endometrial cancer.
Engel BJ,Bowser JL,Broaddus RR,Carson DD
MA513877 was used in immunohistochemistry and western blot to determine that MUC1 stimulates epidermal growth factor receptor expression and function in endometrial cancer
Tue May 31 00:00:00 EDT 2016
Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers.
Brouxhon SM,Kyrkanides S,Teng X,O'Banion MK,Clarke R,Byers S,Ma L
MA5-13877 was used in immunohistochemistry and immunoprecipitation to study targeting sEcad for treatment of breast cancer
Sat Nov 01 00:00:00 EDT 2014
EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling.
Arasada RR,Amann JM,Rahman MA,Huppert SS,Carbone DP
MA5-13877 was used in immunoprecipitation and western blot to examine the effects of kinase inhibtors that target the epidermal growth factor receptor in lung cancer
Wed Oct 01 00:00:00 EDT 2014
Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer.
Molecular medicine (Cambridge, Mass.)
Grivas PD,Day KC,Karatsinides A,Paul A,Shakir N,Owainati I,Liebert M,Kunju LP,Thomas D,Hussain M,Day ML
MA5-13877 was used in western blot to study the efficacy and tolerability of the irreversible tyrosine kinase inhibitor dacomitinib in human bladder cancer models
Fri Nov 08 00:00:00 EST 2013
Activated EGFR stimulates MUC1 expression in human uterine and pancreatic cancer cell lines.
Journal of cellular biochemistry
Engel BJ,Carson DD
MA5-13877 was used in western blot to examine the role that EGFR activation plays in modulating MUC1 levels.
Tue Oct 01 00:00:00 EDT 2013
Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor.
The Journal of biological chemistry
Odintsova E,van Niel G,Conjeaud H,Raposo G,Iwamoto R,Mekada E,Berditchevski F
MA5-13877 was used in immunocytochemistry and western blot to study the modulation of EGFR ubiquitinylation by the CD82 metastasis suppressor
Fri Sep 06 00:00:00 EDT 2013
Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines.
European journal of cancer (Oxford, England : 1990)
Fan P,McDaniel RE,Kim HR,Clagett D,Haddad B,Jordan VC
MA5-13877 was used in western blot to study the influence of estrogen receptor and HER2 expression on the therapeutic efficacy of a c-Src inhibitor in a panel of breast cancer cell lines
Sat Dec 01 00:00:00 EST 2012
The MUC1 Ectodomain: A Novel and Efficient Target for Gold Nanoparticle Clustering and Vapor Nanobubble Generation.
Danysh BP,Constantinou PE,Lukianova-Hleb EY,Lapotko DO,Carson DD
MA5-13877 was used in western blot to assess EGFR and MUC1 as targets for nanoparticle intracellular accumulation and clustering.
Tue Oct 02 00:00:00 EDT 2012
Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action.
Breast cancer research : BCR
DeFazio-Eli L,Strommen K,Dao-Pick T,Parry G,Goodman L,Winslow J
MA5-13877 was used in immunoprecipitation to investigate the state of HER1-HER2 interaction and modification in cell lines and tumors
Fri Apr 15 00:00:00 EDT 2011
A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissue.
Diagnostic molecular pathology : the American journal of surgical pathology, part B
Shi Y,Huang W,Tan Y,Jin X,Dua R,Penuel E,Mukherjee A,Sperinde J,Pannu H,Chenna A,DeFazio-Eli L,Pidaparthi S,Badal Y,Wallweber G,Chen L,Williams S,Tahir H,Larson J,Goodman L,Whitcomb J,Petropoulos C,Winslow J
MA5-13877 was used in immunocytochemistry to develop a novel proximity assay for detecting HER proteins and homodimers in formalin-fixed cell lines and breast tumor tissues
Sun Mar 01 00:00:00 EST 2009
Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.
American journal of physiology. Cell physiology
Deb TB,Coticchia CM,Barndt R,Zuo H,Dickson RB,Johnson MD
MA5-13877 was used in western blot to study the induction of ligand-independent EGFR degradation by the pregnancy-upregulated non-ubiquitous calmodulin kinase
Fri Aug 01 00:00:00 EDT 2008
EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer.
Choi SH,Mendrola JM,Lemmon MA
MA5-13877 was used in western blot to study EGF-independent activation of mutant cell-surface EGF receptors in gefitinib-sensitive lung cancer
Thu Mar 08 00:00:00 EST 2007
Gangliosides play an important role in the organization of CD82-enriched microdomains.
The Biochemical journal
Odintsova E,Butters TD,Monti E,Sprong H,van Meer G,Berditchevski F
MA5-13877 was used in western blot to study the role of gangliosides in membrane micro-domains enriched in the tetraspanin CD82
Fri Dec 01 00:00:00 EST 2006
Microarray analyses in bladder cancer cells: inhibition of hTERT expression down-regulates EGFR.
International journal of cancer
Kraemer K,Schmidt U,Fuessel S,Herr A,Wirth MP,Meye A
MA5-13877 was used in western blot to study the antiproliferative capacity of hTERT antisense oligonucleotides
Fri Sep 15 00:00:00 EDT 2006
Mutations within the kinase domain and truncations of the epidermal growth factor receptor are rare events in bladder cancer: implications for therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Blehm KN,Spiess PE,Bondaruk JE,Dujka ME,Villares GJ,Zhao YJ,Bogler O,Aldape KD,Grossman HB,Adam L,McConkey DJ,Czerniak BA,Dinney CP,Bar-Eli M
MA5-13877 was used in western blot to study the therapeutic implications of mutations and truncations of the EGF receptor in bladder cancer
Tue Aug 01 00:00:00 EDT 2006
ErbB receptor tyrosine kinase network inhibition radiosensitizes carcinoma cells.
International journal of radiation oncology, biology, physics
Contessa JN,Abell A,Valerie K,Lin PS,Schmidt-Ullrich RK
MA5-13877 was used in western blot to study the radiosensitization of carcinoma cells by inhibition of the ErbB receptor tyrosine kinase network by the EGFR-CD533 truncation mutant
Sat Jul 01 00:00:00 EDT 2006
Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation.
Breast cancer research and treatment
Contessa JN,Abell A,Mikkelsen RB,Valerie K,Schmidt-Ullrich RK
MA5-13877 was used in immunoprecipitation to study a novel ErbB3/c-Src signaling pathway that protects carcinoma cells against radiation-induced apoptosis
Sun Jan 01 00:00:00 EST 2006
Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface.
Molecular and cellular biology
Dawson JP,Berger MB,Lin CC,Schlessinger J,Lemmon MA,Ferguson KM
MA5-13877 was used in western blot to study the role of ligand-induced dimer interface conformational changes in the dimerization and activation of EGFR
Thu Sep 01 00:00:00 EDT 2005
Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2.
The Journal of biological chemistry
Sturla LM,Amorino G,Alexander MS,Mikkelsen RB,Valerie K,Schmidt-Ullrichr RK
MA5-13877 was used in immunoprecipitation to study the role of phosphorylation of tyrosines 992 and 1173 in the activation of EGFR by ionizing radiation and the involvement of SHP2
Fri Apr 15 00:00:00 EDT 2005
Src family kinase inhibitors block amphiregulin-mediated autocrine ErbB signaling in normal human keratinocytes.
Kansra S,Stoll SW,Johnson JL,Elder JT
MA5-13877 was used in western blot to study the interplay between Src family kinases and ErbB signaling in normal human keratinocytes
Fri Apr 01 00:00:00 EST 2005
Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle.
Journal of virology
Genther SM,Sterling S,Duensing S,Münger K,Sattler C,Lambert PF
MA5-13877 was used in immunoprecipitation and western blot to study the role of the HPV 16 E5 gene during the productive stage of the viral life cycle
Sat Mar 01 00:00:00 EST 2003