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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 153 of Human EIF5A2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30770 targets EIF5A2 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30770 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 153 of Human EIF5A2.
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
eIF-5A-2; EIF-5A2; eIF5AII; eukaryotic initiation factor 5A; eukaryotic translation initiation factor 5A-2
EIF-5A2; EIF5A2; eIF5AII