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Product Details
H00010136-M02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3G4
Immunogen
ELA3A (AAH07028, 16 a.a. approximately 270 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: SGYGPPSSHS SSRVVHGEDA VPYSWPWQVS LQYEKSGSFY HTCGGSLIAP DWVVTAGHCI SRDLTYQVVL GEYNLAVKEG PEQVIPINSE ELFVHPLWNR SCVACGNDIA LIKLSRSAQL GDAVQLASLP PAGDILPNKT PCYITGWGRL YTNGPLPDKL QQARLPVVDY KHCSRWNWWG STVKKTMVCA GGYIRSGCNG DSGGPLNCPT EDGGWQVHGV TSFVSGFGCN FIWKPTVFTR VSAFIDWIEE TIASH
Target Information
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chymotrypsin-like elastase family member 3A; chymotrypsin-like elastase family, member 3A; elastase 1; elastase 3A, pancreatic; Elastase IIIA; Elastase-3A; Protease E
Gene Aliases: CELA3A; ELA3; ELA3A
UniProt ID: (Human) P09093
Entrez Gene ID: (Human) 10136
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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