Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence of this protein is as follows: SQQPLVWPAW VYCTRYSDRP SSGPRTRKLK KKKNEKEDKR PRTAFTAEQL QRLKAEFQAN RYITEQRRQT LAQELSLNES QIKIWFQNKR AKIKKATGIK NGLALHLMAQ GLYNHSTTTV QDKDESE*
EN1 (Engrailed homolog 1) is a transcription factor expressed in embryonic ventral limb ectoderm and is essential for ventral limb patterning. En1 expression in the developing perichordal tube suggests that it may also be involved in vertebrae assembly. Loss of EN1 function in mice results in dorsal transformations of ventral paw structures and in subtle alterations along the proximal/distal limb axis.
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Protein Aliases: engrailed homolog 1; HME1; Homeobox protein en-1; Homeobox protein engrailed-1; hu-En-1
Gene Aliases: EN1
UniProt ID: (Human) Q05925
Entrez Gene ID: (Human) 2019
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