|Immunohistochemistry (Paraffin) (IHC (P))||10-12.5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from C-terminus of human ERP44 / TXNDC4.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein 44 kDa; ER protein 44; member 10; PDIA10; protein disulfide isomerase family A; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4; TXNDC4
Gene Aliases: ERP44; KIAA0573; PDIA10; TXNDC4; UNQ532/PRO1075
UniProt ID: (Human) Q9BS26
Entrez Gene ID: (Human) 23071
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