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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 69 and 359 of Human ERR alpha|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ChIP assay (ChIP)||Assay-dependent|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28390 targets ERR alpha in WB applications and shows reactivity with Human samples.
The PA5-28390 immunogen is recombinant fragment corresponding to a region within amino acids 69 and 359 of Human ERR alpha.
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ERR-alpha; ERR1; ERRa; ERRalpha; ESRL1; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; estrogen-related receptor alpha; NR3B1; nuclear receptor subfamily 3 group B member 1; steroid hormone receptor ERR1
ERR1; ERRa; ERRalpha; ESRL1; ESRRA; NR3B1