Keep as concentrated solution.
Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Sheep (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%).
Positive Control: H1299, HeLa, HepG2, NIH-3T3, JC, BCL-1, rat liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; Endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER-60 protease; ERp 57; ERp60; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; HIP-70; oxidoreductase ERp57; p58; PDIA 3; phospholipase C, alpha; phospholipase C-alpha; PI PLC; protein disulfide isomerase associated 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; Protein disulfide-isomerase A3; Q-2
Gene Aliases: 58kDa; ER60; Erp; ERP57; ERP60; ERp61; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; PDI; PDI-Q2; PDIA3; PI-PLC; PLC[a]; Plca