|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic Peptide: Q(399) D K I F Q G N K D Y H K D V R N N(416)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4270 detects ESDN from human, mouse and rat samples.
PA1-4270 has been successfully used in Western blot procedures.
PA1-4270 immunizing peptide corresponds to amino acid residues 399-416 from mouse and rat ESDN protein.
A novel protein ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. ESDN is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.