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MA5-12262 targets Exo1 in WB applications and shows reactivity with Human and mouse samples.
The MA5-12262 immunogen is recombinant full length mouse Exo1 protein.
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exonuclease 1; Exonuclease I; hExo1; hExoI; homolog of S. cerevisiae exonuclease 1; mExo1; rad2 nuclease family member; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1
Gene Aliases: 5730442G03Rik; EXO1; EXOI; HEX1; hExoI; Msa
UniProt ID: (Human) Q9UQ84, (Mouse) Q9QZ11
Entrez Gene ID: (Human) 9156, (Mouse) 26909
Molecular Function:
DNA binding protein
damaged DNA-binding protein
endodeoxyribonuclease
exodeoxyribonuclease
hydrolase
nuclease
nucleic acid binding
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