In direct ELISAs, no cross-reactivity with recombinant human (rh) EXTL1, rhEXTL2, rhEXTL3, or recombinant mouse EXTL2 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 22.214.171.124; exostoses-like 1; Exostosin-L; Exostosin-like 1; Exostosin-like 1 (Exostosin-L) (Multiple exostosis-like protein); Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Glucuronosyl-N-acetylglucosaminyl-proteoglycan4-alpha-N-acetylglucosaminyltransferase; MGC70794; multiple exostoses-like 1; Multiple exostosis-like protein
Gene Aliases: D430033M16Rik; Extl1
UniProt ID: (Mouse) Q9JKV7
Entrez Gene ID: (Mouse) 56219
Molecular Function: glycosyltransferase