|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of EphB6 (aa601-750) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15384 targets EhpB6 in IHC and WB applications and shows reactivity with Human samples.
The MA5-15384 immunogen is purified recombinant fragment of EphB6 (aa601-750) expressed in E. Coli.
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EPHB6; Ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
Gene Aliases: EPHB6; HEP
UniProt ID: (Human) O15197
Entrez Gene ID: (Human) 2051
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