|Tested species reactivity||Dog, Cat, Guinea pig, Goat, Human, Sheep, Pig|
|Host / Isotype||Mouse / IgG1|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1:100 - 1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-27129 detects Elastin from human, goat, canine, porcine, ovine, feline, and guinea pig samples.
MA1-27129 has been successfully used in Western blot, immunoprecipitation, and immunohistochemistry (paraffin) procedures. Proteolytic pretreatment is required for immunostaining of paraffin embeded tissue. The positive control of Heart tissue is suggested.
The MA1-27129 immunogen is bovine alpha-Elastin.
This gene encodes a protein that is one of the two components of elastic fibers. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.