The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 98% (by SDS-PAGE).
Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.
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Protein Aliases: C-C motif chemokine 26; CC chemokine IMAC; CCL26; chemokine (C-C motif) ligand 26; chemokine N1; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; PRO242; SCYA26; small inducible cytokine A26; small inducible cytokine subfamily A (Cys-Cys), member 26; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; UNQ216
Gene Aliases: CCL26; Ccl26l; IMAC; MIP-4a; MIP-4alpha; SCYA26; TSC-1; UNQ216/PRO242
UniProt ID: (Human) Q9Y258