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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human EPCAM expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
MA5-15640 targets EPCAM in IHC and WB applications and shows reactivity with Human samples.
The MA5-15640 immunogen is purified recombinant fragment of human EPCAM expressed in E. Coli.
MA5-15640 detects EPCAM which has a predicted molecular weight of approximately 35kDa.
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Epstein-Barr virus-associated lymphoepithelioma-like cholangiocarcinoma: a rare variant of intrahepatic cholangiocarcinoma with favourable outcome.
MA5-15640 was used in immunohistochemistry to report on seven cases of EBV-associated lymphoepithelioma-like cholangiocarcinoma
|Chan AW,Tong JH,Sung MY,Lai PB,To KF||Histopathology (65:674)||2014|
Expression of stemness markers (CD133 and EpCAM) in prognostication of hepatocellular carcinoma.
MA5-15640 was used in immunohistochemistry to study the prognostic value of the immunohistochemical expression of the stemness markers CD133 and EpCAM in hepatocellular carcinoma
|Chan AW,Tong JH,Chan SL,Lai PB,To KF||Histopathology (64:935)||2014|
adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP40; EPCAM; epithelial glycoprotein 314; Epithelial Specific Antigen; ESA; human epithelial glycoprotein-2; KS1/4; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; tumor-associated calcium signal transducer 1
DIAR5; EGP-2; EGP314; EGP40; EPCAM; ESA; GA733-2; HNPCC8; KS1/4; KSA; M1S2; M4S1; MIC18; MK-1; TACSTD1; TROP1